Table 1 lists adverse reactions that occurred in worldwide placebo-controlled clinical trials in 3,419 patients with migraine. No other birth defect was reported for more than 2 infants in this group. While holding your head level, gently breathe in through your nose and out through your mouth for 10 to 20 seconds (see Figure F). The estimated probability of patients taking a second dose or other medication for migraine over the 24 hours following the initial dose of study treatment is summarized in Figure. Concomitant Use with Other Triptans or Ergot Medications Inform patients that use of Imitrex Nasal Spray within 24 hours of another triptan or an ergot-type medication (including dihydroergotamine or methysergide) is contraindicated see Contraindications ( 4 Drug Interactions (.1,.3 ).
Oral administration of sumatriptan to rats prior to and throughout gestation resulted in embryofetal toxicity (decreased body weight, decreased ossification, increased incidence of skeletal abnormalities). The reported rate of major birth defects among deliveries to women with migraine ranged from.2.9 and the reported rate of miscarriage was 17, which were similar to rates reported in women without migraine. The pharmacokinetics of sumatriptan in patients with severe hepatic impairment has not been studied. It is unknown what effect hemodialysis or peritoneal dialysis has on the serum concentrations of sumatriptan. Last reviewed on RxList 12/22/2016, imitrex, nasal.
Imitrex, nasal, spray - FDA prescribing
Talk with your healthcare provider about your chance of having seizures while you take imitrex. Discontinue Imitrex Nasal Spray if these disturbances occur. Your doctor will tell about the frequency and duration of the dose to be taken. See the end of this leaflet for a complete list of ingredients in imitrex.
Dosage Forms and Strengths, unit dose nasal spray devices containing 5 mg or 20 mg sumatriptan. Call your doctor for medical advice about side effects. Tell your doctor all medication and supplements you use. Percentage of Patients with Headache Response (No or Mild Pain) 2 Hours following Treatment imitrex Nasal Spray 5 mg Imitrex Nasal Spray 10 mg imitrex Nasal Spray 20 mg Placebo Trial 1 49a 46a 64a,b,c. Of the 2,257 births with first-trimester exposure to sumatriptan, 107 infants were born with malformations (relative risk.99 95 CI:.91.21).
Imitrex is not used to treat other types of headaches such as hemiplegic (that make you unable to move on one side of your body) or basilar (rare form of migraine with aura) migraines. Headache and Migraine Triggers Slideshow, take the Headaches Quiz Imitrex Nasal Spray Consumer Information Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. When Not To Use Suminat Nasal Spray 20 Gm (Sumatriptan You should avoid Suminat Nasal Spray 20 gm if you: Have ever noticed any Allergy/Hypersensitivity. Anaphylactic/Anaphylactoid Reactions Inform patients that anaphylactic/anaphylactoid reactions have occurred in patients receiving Imitrex Nasal Spray.
Imitrex, nasal : Uses, Side Effects, Interactions
Anaphylactic/Anaphylactoid Reactions Anaphylactic/anaphylactoid reactions have occurred in patients receiving imitrex. There are also reports in patients where no such predisposing factors are apparent. Patient Counseling Information Advise the patient to read the FDA-approved patient labeling (Patient Information). Imitrex can cause serious side effects, including: Heart attack and other heart problems.
With your other hand, hold the container with your thumb supporting the container at the bottom, and your index and middle fingers on either side of the nozzle (see Figure D). Symptoms of peripheral vascular ischemia include: o cramping and pain in your legs or hips o feeling of heaviness or tightness in your leg muscles o burning or aching pain in your feet or toes while resting o numbness. Figure C Figure D Step. For How Long Should You Continue Using Suminat Nasal Spray 20 Gm (Sumatriptan) walnuts, Almonds Help the Hearts of Those With Type 2 Diabetes You are always advised to take Suminat Nasal Spray 20 gm as prescribed by your doctor.
In a trial of 24 male volunteers, the bioavailability relative to subcutaneous injection was low, approximately 17, primarily due to presystemic metabolism and partly due to incomplete absorption. You are not advised to take it in the larger amount or for a longer time than recommended. Imitrex passes into your breast milk. Such reactions can be life-threatening or fatal. See also: Emgality, imitrex Nasal Spray is indicated for the acute treatment of migraine with or without aura in adults. The elimination halflife of sumatriptan is approximately 2 hours see Clinical Pharmacology (.3 and therefore monitoring of patients after overdose with Imitrex Nasal Spray should continue for at least 10 hours or while symptoms or signs persist.
Drug Profiles: imitrex for Migraines Keep, imitrex
It is not known if imitrex is safe and effective to treat cluster headaches. Continue scrolling FOR related article. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat severe dizziness, trouble breathing. It is not known if imitrex can harm your unborn baby. Many people using this medication do not have serious side effects.
Because these effects may be additive, use of ergotamine-containing or ergot-type medications (like dihydroergotamine or methysergide) and Imitrex Nasal Spray within 24 hours of each other is contraindicated. It is not known how using Imitrex Nasal Spray for a long time affects the nose and throat. You should always inform your doctor if you are on other Vitamins, OTC Drugs, or Herbal Supplements. Intranasal sumatriptan has not been evaluated for age differences. Chest, Throat, Neck, and/or Jaw Pain/Tightness/Pressure Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw may occur after treatment with Imitrex Nasal Spray and are usually non-cardiac in origin. About drugs simply
Do not use imitrex if you have: heart problems or a history of heart problems narrowing of blood vessels to your legs, arms, stomach, or kidneys (peripheral vascular disease) uncontrolled high blood pressure severe liver problems hemiplegic migraines or basilar migraines. C.05 in comparison with 5 mg. Patients enrolled in these 5 trials were predominately female (86) and Caucasian (95 with a mean age of 41 years (range: 18 to 65 years). Imitrex Nasal Spray Description Imitrex Nasal Spray contains sumatriptan, a selective 5-HT1B/1D receptor agonist. What Are The Side Effects Of The Suminat Nasal Spray 20 Gm (Sumatriptan) Chest pain Drowsiness Dizziness Shortness of breath Feeling of warmth or heat Irregular heartbeat Itching Numbness Dry mouth Nausea and Vomiting Unusual tiredness and weakness What Are.
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